Dose optimization in gynecological 3D image based interstitial brachytherapy using martinez universal perineal interstitial template (MUPIT) -an institutional experience

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Can combined intracavitary/interstitial approach be an alternative to interstitial brachytherapy with the Martinez Universal Perineal Interstitial Template (MUPIT) in computed tomography-guided adaptive brachytherapy for bulky and/or irregularly shaped gynecological tumors?

BACKGROUND Interstitial brachytherapy (ISBT) is an optional treatment for locally advanced gynecological tumours for which conventional intracavitary brachytherapy (ICBT) would result in suboptimal dose coverage. However, ISBT with Martinez Universal Perineal Interstitial Template (MUPIT), in which ~10-20 needles are usually applied, is more time-consuming and labor-intensive than ICBT alone, m...

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Retrospective analysis of role of interstitial brachytherapy using template (MUPIT) in locally advanced gynecological malignancies.

AIM The aim of this retrospective study was to assess treatment outcomes for patients with locally advanced gynecological malignancies being treated with interstitial brachytherapy using Martinez universal perineal interstitial template (MUPIT) and to study the acute and late sequelae and survival after treatment by this technique. MATERIALS AND METHODS Ninety seven patients untreated with hi...

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Vaginal tolerance of CT based image-guided high-dose rate interstitial brachytherapy for gynecological malignancies

BACKGROUND Purpose of this study was to identify predictors of vaginal ulcer after CT based three-dimensional image-guided high-dose-rate interstitial brachytherapy (HDR-ISBT) for gynecologic malignancies. METHODS Records were reviewed for 44 female (14 with primary disease and 30 with recurrence) with gynecological malignancies treated with HDR-ISBT with or without external beam radiation th...

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Pre-plan technique feasibility in multi-interstitial/endocavitary perineal gynecological brachytherapy

Purpose To present the implementation of a magnetic resonance imaging (MRI) pre-planning technique in multi-interstitial perineal and endocavitary gynecological brachytherapy. Material and methods We used a new fully MRI-compatible applicator that is capable to engage titanium needles, and an intrauterine tandem, developed in our department for the treatment of gynecological cervical cancer p...

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Institutional experience using interstitial brachytherapy for the treatment of primary and recurrent pelvic malignancies

PURPOSE The study assessed the outcomes of patients at a single institution with locally advanced primary and recurrent pelvic malignancies treated with interstitial high-dose-rate (HDR) or low-dose-rate (LDR) brachytherapy (BT), using a modified Syed-Neblett template. MATERIAL AND METHODS Between 1996 and 2010, 60 patients with primary or recurrent pelvic malignancies were treated with inter...

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ژورنال

عنوان ژورنال: Journal of Medical Physics

سال: 2014

ISSN: 0971-6203

DOI: 10.4103/0971-6203.139015